Elevated vitamin B12 levels in autoimmune lymphoproliferative syndrome attributable to elevated haptocorrin in lymphocytes
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منابع مشابه
Elevated Vitamin B12 Blood Levels
But very frequently among those patients, careful inquiries demonstrate that no external human intervention may explain the finding. So we have to find some explanation to the increase within the metabolism. The presence of vitamin B12 in human faeces doesn’t only correspond to what is left from the absorption in the ileum, but it also reflects the production of significant quantities of cobala...
متن کاملElevated Vitamin B12 Blood Levels
But very frequently among those patients, careful inquiries demonstrate that no external human intervention may explain the finding. So we have to find some explanation to the increase within the metabolism. The presence of vitamin B12 in human faeces doesn’t only correspond to what is left from the absorption in the ileum, but it also reflects the production of significant quantities of cobala...
متن کاملEffect of vitamin B12 treatment on haptocorrin.
BACKGROUND Haptocorrin (HC) carries the major part of circulating cobalamin, but whether HC is altered on treatment with vitamin B12 remains unknown. METHODS Our study included 3 populations: a population of vegan men (n = 174; vegan population), of whom 63 were treated daily with 5 mg of oral vitamin B12 for 3 months; a group of patients with a previous methylmalonic acid (MMA) concentration...
متن کاملThe pathophysiology of elevated vitamin B12 in clinical practice.
Hypercobalaminemia (high serum vitamin B12 levels) is a frequent and underestimated anomaly. Clinically, it can be paradoxically accompanied by signs of deficiency, reflecting a functional deficiency linked to qualitative abnormalities, which are related to defects in tissue uptake and action of vitamin B12. The aetiological profile of high serum cobalamin predominantly encompasses severe disea...
متن کاملFunctional Vitamin B12 Deficiency Represented by Elevated Urine Methylmalonic Acid Levels in Patients with Migraine
Materials and Methods: Fifty women having migraine without aura were matched with healthy controls (n=6) with the same age distribution. Fasting serum vitamin B12, folate, plasma total homocysteine (tHcy) and first morning urine methylmalonic acid (MMA) levels were determined in patient and control groups. Statistical differences in laboratory parameters between patient and control groups were ...
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ژورنال
عنوان ژورنال: Clinical Biochemistry
سال: 2012
ISSN: 0009-9120
DOI: 10.1016/j.clinbiochem.2012.01.016